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Finding More Targets for CAR-T Cells
THE SUMMER BEFORE starting sixth grade, in 2006, Taylor Hendrix felt twinges in her right arm and shoulder after swim practice. The 11-year-old from Florence, Alabama, chalked it up to a pulled...
View ArticleMedicare to Cover CAR-T Cell Therapy
IN SEPTEMBER 2018, Janice McClenahan was diagnosed with double-hit lymphoma, a rare type of diffuse large B-cell blood cancer marked by DNA changes in two genes instead of one. The then 73-year-old...
View ArticleSearching the Blood for Signs of Altered Immunity
Larry Saltzman of Sacramento, California, has received two doses of a COVID-19 vaccine. What Saltzman is less sure about is how his immune system responded to his vaccination. In 2010 at age 56,...
View ArticleA Treatment That Came Just in Time
In 2006 at age 46, I was diagnosed with an incurable blood cancer: follicular non-Hodgkin lymphoma, stage IV. For the next 12 years, I was in continuous treatment, never obtaining a complete...
View ArticleCAR T Cells for Blood Cancer Patients
CAR T-CELL THERAPY has emerged as a promising treatment for some types of blood cancer, including large B-cell lymphoma. The treatment involves extracting immune cells from a patient’s body and...
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Control What You Can
IN THE SPRING OF 2016, CICI ROJAS HAD JUST CREATED HER DREAM JOB. She and her husband had started a marketing company focused on Latino consumers. That year, the company was hitting its stride in...
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Taking Stock of CAR T-Cell Therapy
WHEN DOUG OLSON LEARNED in 1996 at the age of 49 that he had chronic lymphocytic leukemia (CLL), he remembers thinking he wasn’t going to make it. “Being told you have cancer is terrifying,” he says....
View ArticleLosing Heart
FOR PEOPLE DIAGNOSED WITH HODGKIN LYMPHOMA, there’s good news and bad news. Death rates for Hodgkin lymphoma have declined since the mid-1970s—thanks in part to combination chemotherapy and radiation...
View ArticleTangled Family Ties
NOT EVERY CHILDHOOD CONJURES UP happy memories. For Susan Keller and her three brothers, who grew up with an abusive mother and an alcoholic father who abandoned the family when Keller was 12,...
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Living With Chronic Blood Cancer
TOWARD THE END OF 2014, 52-year-old Doreen Zetterlund was experiencing muscle spasms in her neck and shoulders. She also had a lump on the side of her neck but chalked up her symptoms to stress. When...
View ArticleCAR T-cell Therapy: Understanding the Warning and the Risks
CHIMERIC ANTIGEN RECEPTOR (CAR) T-CELL THERAPY, a personalized form of immunotherapy that modifies a patient’s immune system to target and kill cancer cells, has been lifesaving for many people with...
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